Chemicals Selected by OEHHA for Consideration for Listing by the Carcinogen Identification Committee and Request for Relevant Information on the Carcinogenic Hazards of these Chemicals

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of Proposition 65[1].  The Carcinogen Identification Committee (CIC) of OEHHA’s Science Advisory Board serves as the state’s qualified experts and renders an opinion about whether a chemical has been clearly shown to cause cancer[2].  The chemicals identified as carcinogens by the CIC are added to the Proposition 65 list. 

OEHHA has selected the chemicals below for the CIC’s review for possible listing under Proposition 65.  OEHHA is initiating the development of hazard identification materials on these chemicals. 

Chemicals Selected for Preparation of Cancer Hazard Identification Materials



Gentian violet




By this notice, OEHHA is giving the public an opportunity to provide information relevant to the assessment of the evidence of carcinogenicity for gentian violet and      N-nitrosohexamethyleneimine.  Relevant information includes but is not limited to: 

  • Cancer bioassays
  • Cancer epidemiological studies
  • Genotoxicity testing
  • Other pertinent data on:
    • Pharmacokinetics
    • Biomarkers
    • Effects on biochemical and physiological processes in humans 

Interested parties wishing to provide such information should send it to the address given below. 

The publication of this notice marks the start of a 45-day data call-in period, ending on Monday, May 21, 2018.  The information received during this period will be reviewed and considered by OEHHA as it prepares the cancer hazard identification materials on these chemicals. 

These chemicals were selected using the procedure described in a document entitled: “Process for Prioritizing Chemicals for Consideration under Proposition 65 by the State’s Qualified Experts.”  This document is available on the Internet at

OEHHA selected these chemicals from those prioritized by the CIC in 2009 and 2010.   

Hazard identification materials for each of these chemicals will be presented at future meetings of the CIC for consideration of listing under Proposition 65.  As of the release of this notice, these meetings have not been scheduled.

Hazard identification materials are made available to the public for comment prior to the CIC’s consideration of the chemical(s) for possible listing.  The availability of hazard identification materials will be announced in the California Regulatory Notice Register and on OEHHA’s website.  Public comments received on these materials are sent to the CIC for its consideration prior to the meeting at which the chemical(s) will be considered for listing.  OEHHA announces the time, date, location, and agenda of CIC meetings in the California Regulatory Notice Register and on its website. 

We encourage you to submit relevant information responsive to this request in electronic form, rather than in paper form.  Comments may be submitted electronically through our website at  Comments submitted in paper form can be mailed, faxed, or delivered in person to the addresses below:

Mailing Address:  

Ms. Michelle Ramirez
Office of Environmental Health Hazard Assessment
Proposition 65 Implementation
P.O. Box 4010, MS-12B
Sacramento, California 95812-4010

Fax: (916) 323-2265      

Street Address: 
1001 I Street
Sacramento, California 95814

In order to be considered at this point in the process, the relevant information must be received at OEHHA by 5:00 p.m. on Monday, May 21, 2018.

Footnotes and References

[1] The Safe Drinking Water and Toxic Enforcement Act of 1986, codified at Health and Safety Code section 25249.5 et seq.

[2] Title 27, Cal. Code of Regs., section 25302 et seq.